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Antigenic Specificity | MAP Kinase, p44/42 (Erk1/Erk2, Extracellular Signal Regulated Kinase) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | hamster, human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of total human p44/42 MAP kinase (Erk1/Erk2) protein. In some cell types, recognizes p44 MAPK more readily than p42 MAPK. Does not recognize JNK/SAPK nor p38 MAP kinase. Species Crossreactivity: Human, mouse, rat, hamster, zebrafish. Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. MAP kinases are activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters. Activation of MAP kinases occurs through phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T* |
Immunogen | Immunogen: Synthetic peptide derived from the sequence in the C-terminus of rat p42 MAP kinase, coupled to KLH. |
Other Names | [-MAP Kinase, p44/42 (Erk1/Erk2, Extracellular Signal Regulated Kinase)], [MAPK1] |
Gene, Accession # | Gene ID: 373953, NCBI: NP_989481.1 |
Catalog # | MBS614655 |
Price | $550 |
Order / More Info | MAP Kinase, p44/42 (Erk1/Erk2, Extracellular Signal Regulated Kinase) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |