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Antigenic Specificity | SNCA (C-term), 104-133 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: porcine, bovine, monkey) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SNCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the C-terminal region of human SNCA. Alpha Synuclein is implicated in the regulation of dopamine release and transport. It is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). In the nervous system, alpha Synuclein is primarily located at presynaptic terminals and is found membrane bound in dopaminergic neurons. It can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies), including Parkinson's Disease. Alpha Synuclein induces fibri |
Immunogen | n/a |
Other Names | [Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; SNCA; NACP; PARK1] |
Gene, Accession # | [SNCA], Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840 |
Catalog # | MBS9210587 |
Price | $165, $370 |
Order / More Info | SNCA (C-term), 104-133 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kumru, H., et al., Ann. Neurol. 56(4):599-603 (2004). Pigullo, S., et al., Parkinsonism Relat. Disord. 10(6):357-362 (2004). Yao, D., et al., Proc. Natl. Acad. Sci. U.S.A. 101(29):10810-10814 (2004). West, A.B., et al., J. Biol. Chem. 279(28):28896-28902 (2004). Wang, F., et al., Genes Chromosomes Cancer 40(2):85-96 (2004). |