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Antigenic Specificity | STEAP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total STEAP3 protein. Caspases modulate apoptosis in various ways. Specifically, Caspase-3, a death protease, is instrumental in cleaving cellular proteins, dismantling the cell and forming apoptotic bodies. pHyde has a potential role as a tumor suppressor by inducing caspase-3-mediated apoptosis and stimulating p53 expression. A dose-dependent increase in caspase-3 activity is observed in transduced pHyde DU145 cells. Furthermore, caspase-3 may be necessary for pHyde-mediated apoptosis. The pHyde gene may upregulate the apoptosis pathway and thus have a potential application in cancer gene therapy. Recombinant pHyde inhibits the growth of human prostate cancer cell lines DU145 and LNCaP in vitro. DU |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human STEAP3. |
Other Names | [STEAP3; STMP3; TSAP6; dudlin-2] |
Gene, Accession # | [STEAP3], Gene ID: 55240, NCBI: NP_001008410.1, UniProt: Q658P3 |
Catalog # | MBS9407492 |
Price | $255 |
Order / More Info | STEAP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |