LRP5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLRP5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunoprecipitation
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DescriptionThis antibody recognizes ~175 kDa of human LRP5 protein. It also reacts with mouse and rat. The other species are not tested. Low-desnsity lipoprotein receptor (LDLR)-related protein 5 (LRP5) is a member of the LDLR family which consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LRP5 causes several human diseases including bone mineral density variability1, endosteal hyperostosis, autosomal dominant osteopetrosis type I etc. The V171 mutation in LRP5 causes high bone density by impairing the action of a normal antagonist of the Wnt pathway and thus increasing Wnt signaling. The activity of LRP5 and LRP6 can be inhibited by binding of some members of Dickkopf (DKK) family proteins. Upon stimulati
ImmunogenAntigen Preparation: A synthetic peptide corresponding to the epitope KATLY of human LRP5 protei
Other Names[Rabbit LRP5; Low-density lipoprotein Receptor-related Protein 5 (LRP5)], [LRP5; LRP5; HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; OPTA1; VBCH2; LRP7]
Gene, Accession #[LRP5 (Non-phospho)], Gene ID: 4041, NCBI: NP_002326.2, UniProt: O75197
Catalog #MBS462067
Price$285
Order / More InfoLRP5 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZahid Khan et al. (2007), Molecular and Cellular Biology, 27 (20), 7291-7301.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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