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Antigenic Specificity | IL-17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these dis |
Immunogen | Immunogen: IL-17 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-17A. Buffer: IL-17 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-17; IL17; CTLA8; IL-17; IL-17A; IL17; Interleukin-17A; Cytotoxic T-lymphocyte-associated antigen 8; interleukin 17A], [IL17A; IL17A; IL17; CTLA8; IL-17; IL-17A; CTLA8; IL17; IL-17; IL-17A; CTLA-8] |
Gene, Accession # | [IL17A], Gene ID: 3605, NCBI: NP_002181, UniProt: Q16552 |
Catalog # | MBS150429 |
Price | $375 |
Order / More Info | IL-17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |