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Antigenic Specificity | SUN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex |
Immunogen | Immunogen: Recombinant Human SUN domain-containing protein 2 protein (45-155AA) |
Other Names | [SUN domain-containing protein 2; Protein unc-84 homolog B; Rab5-interacting protein; Rab5IP; Sad1/unc-84 protein-like 2; SUN2; FRIGG; KIAA0668; RAB5IP; UNC84B] |
Gene, Accession # | [SUN2], Gene ID: 25777, NCBI: NP_001186508.1, UniProt: Q9UH99 |
Catalog # | MBS7109581 |
Price | $160, $235 |
Order / More Info | SUN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |