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Antigenic Specificity | ITM2C - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against ITM2C. It was validated on Western BlotTarget Description: ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation. |
Immunogen | n/a |
Other Names | [integral membrane protein 2C isoform 1; Integral membrane protein 2C; integral membrane protein 2C; integral membrane protein 2C; Cerebral protein 14; Transmembrane protein BRI3CT-BRI3] |
Gene, Accession # | [ITM2C], Gene ID: 81618, NCBI: NP_112188, UniProt: Q9NQX7 |
Catalog # | MBS3207462 |
Price | $335 |
Order / More Info | ITM2C - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |