DR5 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | DR5 |
| Clone | [7F4-F8-G11] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous levels of TNFRSF10B and does not cross-react with related proteins. Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Essential for ER stress-induced apoptosis. |
| Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Purified recombinant human TNFRSF10B protein fragments expressed in E Coli. |
| Other Names | [Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L] |
| Gene, Accession # | [DR5], Gene ID: 8795, NCBI: NP_003833.4, UniProt: O14763 |
| Catalog # | MBS9400153 |
| Price | $200, $255 |
| Order / More Info | DR5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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