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Antigenic Specificity | Human CD226 |
Clone | [DX11] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | no preservative |
Size | 1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Flow cytometry (FC/FACS), Functional Assays (FN), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD226 antibody, clone DX11 recognizes human CD226, a 65kDa glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Mouse anti Human CD226 antibody, clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells (Kojima et al. 2003). |
Immunogen | Immunogen: Human cytotoxic T lymphocyte clone Fusion Partners: Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [CD226 antigen isoform a; CD226 antigen; CD226 antigen; DNAX accessory molecule 1; DNAX accessory molecule-1; T lineage-specific activation antigen 1 antigen; adhesion glycoprotein; platelet and T cell activation antigen 1; CD226 molecule; DNAX accessory molecule 1; DNAM-1; CD_antigen: CD226], [CD226; CD226; PTA1; DNAM1; DNAM-1; TLiSA1; DNAM1; DNAM-1] |
Gene, Accession # | [CD226], Gene ID: 10666, NCBI: NP_006557.2, UniProt: Q15762 |
Catalog # | MBS210234 |
Price | $675 |
Order / More Info | Human CD226 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |