Phospho-TNFR (S274) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-TNFR (S274)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis TNFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human TNFR. A member of the TNF-receptor superfamily, this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant pe
Immunogenn/a
Other Names[Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD120a; Tumor necrosis factor receptor superfamily member 1A; membrane form; Tumor necrosis factor-binding protein 1; TBPI; TNFRSF1A; TNFAR; TNFR1]
Gene, Accession #[TNFRSF1A], Gene ID: 7132, NCBI: NP_001056.1, UniProt: P19438
Catalog #MBS9211248
Price$165, $370
Order / More InfoPhospho-TNFR (S274) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKuo, N.W., et al., Invest. Ophthalmol. Vis. Sci. 46(5):1565-1571 (2005). Siebert, S., et al., Arthritis Rheum. 52(4):1287-1292 (2005). Spahr, L., et al., J. Hepatol. 41(2):229-234 (2004). Wang, W.H., et al., Mol. Cell. Biol. 24(23):10352-10365 (2004). Tashiro, H., et al., Transpl. Int. 17(10):626-633 (2004).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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