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Antigenic Specificity | ZFYVE27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZFYVE27 antibody detects endogenous levels of ZFYVE27. Function: Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (PubMed:17082457). Promotes axonal elongation and contributes to the establishment of neuronal cell polarity (By similarity). Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner (PubMed:19289470). Contributes to both the formation and stabilization of the tubular ER network (PubMed:24668814). Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections (PubMed:23969831). Acts as an adapter protein and facilitates the interaction of KIF5A with VAPA, VAPB, SUR |
Immunogen | Immunogen: A synthesized peptide derived from human ZFYVE27. Subcellular Location: Recycling Endosome Membrane. Endoplasmic Reticulum Membrane. Cell Projection > Growth Cone Membrane. Cell Membrane. Localizes at both dendrites and axons. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (91%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (91%) |
Other Names | [Protrudin; RP11 459F3.2; SPG33; ZFY27_HUMAN; ZFYVE27; zinc finger FYVE domain containing 27; Zinc finger FYVE domain containing protein 27; Zinc finger FYVE domain-containing protein 27] |
Gene, Accession # | [ZFYVE27], Gene ID: 118813, NCBI: NP_001002261.1, UniProt: Q5T4F4 |
Catalog # | MBS9603736 |
Price | $240, $280 |
Order / More Info | ZFYVE27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |