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Antigenic Specificity | Human CD62L |
Clone | [DREG56] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
Immunogen | n/a |
Other Names | [Human CD62L; L-selectin; Sell; CD62 antigen-like family member L; LAM-1; LECAM1; Lymph node homing receptor; Ly-22; CD62L; Lnhr; Ly22] |
Gene, Accession # | [CD62L], Gene ID: 6402, NCBI: NP_000646.2, UniProt: P14151 |
Catalog # | MBS2553831 |
Price | $70, $105 |
Order / More Info | Human CD62L Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kishimoto T, et al. 1990. P. Natl. Acad. Sci. USA 87:2244. 2. Kishimoto T, et al. 1991. Blood 78:805. |