Human CD62L Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD62L
Clone[DREG56]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Western Blot (WB)
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DescriptionCD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Immunogenn/a
Other Names[Human CD62L; L-selectin; Sell; CD62 antigen-like family member L; LAM-1; LECAM1; Lymph node homing receptor; Ly-22; CD62L; Lnhr; Ly22]
Gene, Accession #[CD62L], Gene ID: 6402, NCBI: NP_000646.2, UniProt: P14151
Catalog #MBS2553831
Price$70, $105
Order / More InfoHuman CD62L Antibody from MYBIOSOURCE INC.
Product Specific References1. Kishimoto T, et al. 1990. P. Natl. Acad. Sci. USA 87:2244. 2. Kishimoto T, et al. 1991. Blood 78:805.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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