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Antigenic Specificity | BARD1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against BARD1. It was validated on Western BlotTarget Description: This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex be |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human BARD1 |
Other Names | [BRCA1-associated RING domain protein 1 isoform 1; BRCA1-associated RING domain protein 1; BRCA1 associated RING domain 1] |
Gene, Accession # | [BARD1], Gene ID: 580, NCBI: NP_000456.2, UniProt: F6MDH8 |
Catalog # | MBS3206632 |
Price | $335 |
Order / More Info | BARD1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |