VISTA/GI24 (Negative Regulator of Immune Response) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-VISTA/GI24 (Negative Regulator of Immune Response) antibody, protein, ELISA kits.
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| Antigenic Specificity | VISTA/GI24 (Negative Regulator of Immune Response) |
| Clone | [VISTA/2864] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: VISTA/GI24 is a transmembrane protein expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESC s, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Mature human Gi24 contains a 162aa extracellular region with one V-type Ig-like domain and a 96aa cytoplasmic domain. Human Gi24 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30kDa extracellular fragment plus a 25-30kDa membrane-bound fragment. VISTA is a negative checkpoint regulator and is |
| Immunogen | Immunogen: Recombinant full-length human VISTA protein |
| Other Names | [B7H5; DD1alpha; GI24; PD-1H; PDCD1 homolog; Platelet receptor Gi24; PP2135;Stress-induced secreted protein 1 (SISP1); V domain Ig suppressor of T cell activation;V Set Immuno-regulatory Receptor] |
| Gene, Accession # | [VISTA/GI24], Gene ID: 64115, NCBI: NP_071436.1, UniProt: Q9H7M9 |
| Catalog # | MBS4381245 |
| Price | $190, $340, $340 |
| Order / More Info | VISTA/GI24 (Negative Regulator of Immune Response) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lines, J.L., et al. Cancer Immunol Res. 2014;2(6):510-517. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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