MCC Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | MCC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Colorectal mutant cancer protein(MCC) detection. Tested with WB in Human, Mouse, Rat. Background: MUTATED IN COLORECTAL CANCERS(MCC) is a tumor suppressor gene. It is mapped to 5q22.2. This gene suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. MCC also Inhibits DNA binding of b-catenin/TCF/LEF transcription factors, and it is Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase(PAK) activation. What's more, MCC can interact with SCRIB(via phosphorylated PDZ-binding motif), EZR, SNX27, SLC9A3R1 and SLC9A3R2. |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MCC (573-590aa IQQLKNDRAAVKLTMLEL), identical to the related mouse and rat sequences. |
| Other Names | [Colorectal mutant cancer protein; mutated in colorectal cancers; Colorectal mutant cancer protein; CRCM_HUMAN; DKFZp762O1615; FLJ38893; FLJ46755; MCC 1; MCC; MCC1; Mutated in colorectal cancers; Protein MCC], [MCC; MCC; MCC1; Protein MCC] |
| Gene, Accession # | [MCC], Gene ID: 4163, NCBI: P23508.2, UniProt: P23508 |
| Catalog # | MBS177086 |
| Price | $280 |
| Order / More Info | MCC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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