CD177 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD177
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: CD177 Polyclonal Antibody detects endogenous levels of CD177 protein. CD177 encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
ImmunogenImmunogen: Synthesized peptide derived from the internal region of human CD177
Other Names[Rabbit CD177; CD177; NB1; PRV1; CD177 antigen; Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD177]
Gene, Accession #[CD177], Gene ID: 57126, NCBI: NP_065139.2, UniProt: Q8N6Q3
Catalog #MBS9703672
Price$130, $220, $325
Order / More InfoCD177 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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