Estrogen Receptor Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEstrogen Receptor
Clone[TE111.5D11]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, sheep, rabbit, hamster, cow, porcine, dog, chicken
IsotypeIgG1
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Gel Supershift (GS), Binding Blocking, Chromatin Precipitation
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DescriptionThe estrogen receptor (ER) gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
ImmunogenImmunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with the 35 kDa C-terminal fragment (aa 302-595) of human ER expressed in E. coli and mouse myeloma cells.
Other Names[steroid hormone receptor ERR1; Steroid hormone receptor ERR1; steroid hormone receptor ERR1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1; estrogen-related receptor alpha; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1], [ESRRA; ESRRA; ERR1; ERRa; ESRL1; NR3B1; ERRalpha; ERR1; ESRL1; NR3B1; ERR-alpha]
Gene, Accession #Gene ID: 2101, NCBI: NP_004442.3, UniProt: P11474
Catalog #MBS395056
Price$550
Order / More InfoEstrogen Receptor Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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