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Antigenic Specificity | Estrogen Receptor |
Clone | [TE111.5D11] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, sheep, rabbit, hamster, cow, porcine, dog, chicken |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Gel Supershift (GS), Binding Blocking, Chromatin Precipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The estrogen receptor (ER) gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. |
Immunogen | Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with the 35 kDa C-terminal fragment (aa 302-595) of human ER expressed in E. coli and mouse myeloma cells. |
Other Names | [steroid hormone receptor ERR1; Steroid hormone receptor ERR1; steroid hormone receptor ERR1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1; estrogen-related receptor alpha; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1], [ESRRA; ESRRA; ERR1; ERRa; ESRL1; NR3B1; ERRalpha; ERR1; ESRL1; NR3B1; ERR-alpha] |
Gene, Accession # | Gene ID: 2101, NCBI: NP_004442.3, UniProt: P11474 |
Catalog # | MBS395056 |
Price | $550 |
Order / More Info | Estrogen Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |