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Antigenic Specificity | S1PR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent |
Immunogen | Immunogen: Recombinant human Sphingosine 1-phosphate receptor 1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31625 / sc-16070 / sc-25489 |
Other Names | [Sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P1; Endothelial differentiation G-protein coupled receptor 1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1; S1PR1; CHEDG1; EDG1], [S1PR1; S1PR1; EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362; CHEDG1; EDG1; S1P receptor 1; S1P1; S1P receptor Edg-1] |
Gene, Accession # | [S1PR1], Gene ID: 1901, NCBI: NP_001391.2, UniProt: P21453 |
Catalog # | MBS1492786 |
Price | $160, $235 |
Order / More Info | S1PR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |