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Antigenic Specificity | IREB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IREB2 (NP 004127.1). |
Other Names | [ACO3; IRP2; IRP2AD; IRE-BP2; IRE-BP 2] |
Gene, Accession # | [IREB2], NCBI: NP_004127.1, UniProt: P48200 |
Catalog # | MBS8546058 |
Price | $280 |
Order / More Info | IREB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |