IL17A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IL17A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: IL17A antibody detects endogenous levels of total IL17A. Description: IL-17A is a cystine-linked homodimeric pro-inflammatory cytokine produced by Th17 cells, a distinct CD4+ T cell lineage (1, 2). IL-17A stimulates the production of the pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-6. IL-17A also induces production of the neutrophil chemoattractants IL-8, CXCL1, and CXCL6 thereby bridging adaptive and innate immunity (1, 2). IL-17A is intimately involved in mucosal immunity against bacterial infections (1, 3) and has a putative role in some autoimmune disorders (1, 4). IL-17A effects appear to be exerted primarily through binding to the IL-17RA (5). IL-17A binding induces production of cytokines, chemokines and other |
| Immunogen | Immunogen: A synthesized peptide derived from human IL17A Subcellular Location: Secreted. Tissue Specificity: Restricted to activated memory T-cells. |
| Other Names | [CTLA 8; CTLA-8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL 17A; IL-17; IL-17A; IL17; IL17_HUMAN; Il17a; Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); Interleukin 17A; Interleukin-17A; Interleukin17; Interleukin17A; OTTHUMP00000016597; OTTMUSP00000046003] |
| Gene, Accession # | [IL17A], Gene ID: 3605, NCBI: NP_002181.1, UniProt: Q16552 |
| Catalog # | MBS9606787 |
| Price | $240, $280 |
| Order / More Info | IL17A Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wang S, Wei J, Fan Y, Ding H, Tian H, Zhou X, Cheng L; Journal: Inflammation. Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways. Zhong W, Gao L, Zhou Z, Lin H, Chen C, Huang P, Huang W, Zhou C, Huang S, Nie L, Liu Y, Chen Y, Zhou D, Lv Z; Journal: Oncotarget. Indoleamine 2, 3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2, 3-dioxygenase compensation. Yan J, Yang X, Han D, Feng J; Journal: Mol Med Rep. Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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