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Antigenic Specificity | APBA2BP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein. The protein encoded by NECAB3 interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein (N-terminal EF-hand calcium binding protein 3), together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been foun |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human APBA2BP at AA range: 290-370 |
Other Names | [Rabbit APBA2BP; NECAB3; APBA2BP; NIP1; SYTIP2; XB51; N-terminal EF-hand calcium-binding protein 3; Amyloid beta A4 protein-binding family A member 2-binding protein; Nek2-interacting protein 1; Neuronal calcium-binding protein 3; X11L-binding protein 51] |
Gene, Accession # | [APBA2BP], Gene ID: 63941, NCBI: NP_112508.3, UniProt: Q96P71 |
Catalog # | MBS9701406 |
Price | $130, $220, $325 |
Order / More Info | APBA2BP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |