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Antigenic Specificity | Human karyopherin (importin) beta 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.15 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Target Names: KPNB1. Target Details: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein |
Immunogen | Immunogen: Human KPNB1. Species: Homo sapiens (Human). Product Type: Purified Rabbit Anti human PolyClonal Antibody |
Other Names | n/a |
Gene, Accession # | UniProt: Q14974 |
Catalog # | MBS713065 |
Price | $230, $500 |
Order / More Info | Human karyopherin (importin) beta 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |