DNMT3A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDNMT3A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionMethylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development (1,2). Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3 (1,2). DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication. DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues. DNMT3A and DNMT3B function as de novo methyltransferases that methylate previously unmethylated regions of DNA. DNMT2 is expressed at low l
ImmunogenImmunogen: Recombinant Protein
Other Names[DNMT3A2; M.HsaIIIA], [DNMT3A; DNMT3A; TBRS; DNMT3A2; M.HsaIIIA; Dnmt3a; DNA MTase HsaIIIA; M.HsaIIIA]
Gene, Accession #[DNMT3A], Gene ID: 1788, NCBI: Q9Y6K1.4, UniProt: Q9Y6K1
Catalog #MBS126567
Price$200, $275, $430
Order / More InfoDNMT3A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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