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Antigenic Specificity | EGFR (N-term), 259-287 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: chicken, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.4 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR. The protein encoded by this gene is a transmembraneglycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growthfactor family. EGFR is a cell surface protein that binds toepidermal growth factor. Binding of the protein to a ligand inducesreceptor dimerization and tyrosine autophosphorylation and leads tocell proliferation. Mutations in this gene are associated with lungcancer. Multiple alternatively spliced transcript variants thatencode different protein isoforms have been found for |
Immunogen | n/a |
Other Names | [Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR; ERBB; ERBB1; HER1] |
Gene, Accession # | [EGFR], Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533 |
Catalog # | MBS9209832 |
Price | $165, $370 |
Order / More Info | EGFR (N-term), 259-287 Antibody from MYBIOSOURCE INC. |
Product Specific References | Abdallah, R.T., et al. J. Biol. Chem. 285(45):35206-35215(2010) Lu, C., et al. Mol. Cell. Biol. 30(22):5432-5443(2010) Rosell, R., et al. Ann. N. Y. Acad. Sci. 1210, 45-52 (2010) : Hata, A., et al. J Thorac Oncol 5(10):1524-1528(2010) Aguirre, A., et al. Nature 467(7313):323-327(2010) |