EGFR (N-term), 259-287 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEGFR (N-term), 259-287
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: chicken, mouse)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.4
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR. The protein encoded by this gene is a transmembraneglycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growthfactor family. EGFR is a cell surface protein that binds toepidermal growth factor. Binding of the protein to a ligand inducesreceptor dimerization and tyrosine autophosphorylation and leads tocell proliferation. Mutations in this gene are associated with lungcancer. Multiple alternatively spliced transcript variants thatencode different protein isoforms have been found for
Immunogenn/a
Other Names[Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR; ERBB; ERBB1; HER1]
Gene, Accession #[EGFR], Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533
Catalog #MBS9209832
Price$165, $370
Order / More InfoEGFR (N-term), 259-287 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAbdallah, R.T., et al. J. Biol. Chem. 285(45):35206-35215(2010) Lu, C., et al. Mol. Cell. Biol. 30(22):5432-5443(2010) Rosell, R., et al. Ann. N. Y. Acad. Sci. 1210, 45-52 (2010) : Hata, A., et al. J Thorac Oncol 5(10):1524-1528(2010) Aguirre, A., et al. Nature 467(7313):323-327(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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