CYP1B1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CYP1B1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Cytochrome P450 1B1(CYP1B1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. CYP1B1 belongs to the the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a |
| Immunogen | Immunogen: E Coli-derived human CYP1B1 recombinant protein (Position: R255-L480). Human CYP1B1 shares 85.4% and 84.5% amino acid (aa) sequence identity with mouse and rat CYP1B1, respectively. Ig Type: Rabbit IgG |
| Other Names | [Cytochrome P450 1B1; Aryl hydrocarbon hydroxylase; CP1B; CP1B1_HUMAN; Cyp1b1; CYPIB1; Cytochrome P450 1B1; Cytochrome P450 family 1 subfamily B polypeptide 1; Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile); Flavoprotein linked monooxygenase; GLC3A; Microsomal monooxygenase; P4501B1; Xenobiotic monooxygenase; cytochrome P450, family 1, subfamily B, polypeptide 1], [CYP1B1; CYP1B1; CP1B; GLC3A; CYPIB1; P4501B1] |
| Gene, Accession # | [CYP1B1], Gene ID: 1545, NCBI: NP_000095.2, UniProt: Q16678 |
| Catalog # | MBS178206 |
| Price | $315 |
| Order / More Info | CYP1B1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: cytochrome P450. 2. Bailey LR, Roodi N, Dupont WD, Parl FF (1998). Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.. Cancer Res. 58 (22): 5038-41. 3. Michels-Rautenstrauss KG, Mardin CY, Zenker M et al. (2002). Primary congenital glaucoma: three case reports on novel mutations and combinations of mutations in the GLC3A (CYP1B1) gene.. J. Glaucoma 10 (4): 354-7. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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