ASC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityASC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionApoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4). Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide corresponding to amino acids 182 to 195 of human ASC.
Other Names[apoptosis-associated speck-like protein containing a CARD; Apoptosis-associated speck-like protein containing a CARD; apoptosis-associated speck-like protein containing a CARD; PYD and CARD domain containing; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1]
Gene, Accession #[ASC], Gene ID: 29108, NCBI: BAA87339
Catalog #MBS9401386
Price$320
Order / More InfoASC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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