SUV39H1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SUV39H1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SUV39H1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SUV39H1 antibody detects endogenous levels of total SUV39H1. Function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. Also weakly methylates histone H1 (in vitro). H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 an |
| Immunogen | Immunogen: A synthesized peptide derived from human SUV39H1 Subcellular Location: Nucleus. Nucleus Lamina. Nucleus, Nucleoplasm. Chromosome, Centromere. Associates with centromeric constitutive heterochromatin. Tissue Specificity: Accumulates during mitosis at centromeres during prometaphase, but dissociates from the centromere at the meta-to anaphase transition. Predicted Cross Reactivity: Pig, Bovine, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Rabbit (100%), Dog (100%) |
| Other Names | [H3 K9 HMTase1; H3-K9-HMTase 1; Histone H3-K9 methyltransferase 1; Histone H3-K9 methyltransferase1; Histone lysine N methyltransferase, H3 lysine 9 specific 1; Histone-lysine N-methyltransferase SUV39H1; KMT1 A; KMT1A; Lysine N methyltransferase 1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; Su(var)3 9 homolog 1; Su(var)3-9 homolog 1; Suppressor of variegation 3 9 homolog 1 (Drosophila); Suppressor of variegation 3-9 homolog 1; SUV39 H1; SUV39H; SUV39H1; SUV91_HUMAN] |
| Gene, Accession # | [SUV39H1], Gene ID: 6839, NCBI: NP_001269095.1, UniProt: O43463 |
| Catalog # | MBS9608805 |
| Price | $240, $280 |
| Order / More Info | SUV39H1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies