MMP3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMMP3
Clone[MMP3/1994R]
Host SpeciesRabbit
Reactive Specieshuman.
IsotypeIgG
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin-fixed
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DescriptionThe matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and hea
ImmunogenImmunogen: Recombinant fragment of human MMP3 protein (around aa 317-327) Cellular Localization: Cytoplasm, extracellular matrix.
Other Names[CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; MMP3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1]
Gene, Accession #[MMP3], Gene ID: 4314, NCBI: NP_002413.1, UniProt: P08254
Catalog #MBS4380112
Price$190, $340, $340
Order / More InfoMMP3 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesShur, S.A., et al. 1983. The role of cysteinyl residues in the phosphorylase kinase activity as revealed by iodacetamide modification. Biochem. Int. 7: 197-206
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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