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Antigenic Specificity | Elastin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Elastin antibody detects endogenous levels of total Elastin. Function: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).Subunit Structure: The polymeric elastin chains are cross-linked together into an extensible 3D network. Forms a ternary complex with BGN and MFAP2. Interacts with MFAP2 via divalent cations (calcium > magnesium > manganese) in a dose-dependent and saturating manner. Interacts with FBLN5 (PubMed:15790312, PubMed:17035250). Interacts with FBN1 (PubMed:15790312). F |
Immunogen | Immunogen: A synthesized peptide derived from human Elastin Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Extracellular matrix of elastic fibers. Tissue Specificity: Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin. |
Other Names | [Elastin; ELN; ELN_HUMAN; SVAS; Tropoelastin; WBS; WS] |
Gene, Accession # | [ELN], Gene ID: 2006, NCBI: NP_000492.2, UniProt: P15502 |
Catalog # | MBS9608200 |
Price | $240, $280 |
Order / More Info | Elastin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |