TLR4/MD-2, Human Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR4/MD-2, Human
Clone7E3
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionProduct Description: The monoclonal antibody 7E3 reacts with the Toll-like receptor 4 (TLR4, CD284)/MD-2 complex. TLRs belong to a family of proteins that specifically recognizes and senses microbial products. They are highly conserved throughout evolution and act as innate immune recognition receptors against many pathogens. TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. MD-2 exists as a cell surface protein in association with TLR4. It also exists as secreted forms consisting of MD-2 monomers and multimers (sMD-2). Circulating sMD-2 is mainly present as a doublet of ~20 and 25 kD, representing differentially gly
ImmunogenImmunogen: TLR4/MD-2 expressing CHO cells/ chimeric TLR4/MD-2 fusion protein
Other Namesn/a
Gene, Accession #[TLR4/MD-2]
Catalog #MBS584320
Price$535
Order / More InfoTLR4/MD-2, Human Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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