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Antigenic Specificity | RAB11FIP5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAB11FIP5 antibody detects endogenous levels of total RAB11FIP5. Function: Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.Subunit Structure: Forms a heterooligomeric complex with RAB11FIP4. Binds NAPG and TROVE2. Binds RAB11A that has been activated by GTP binding.Post-translational Modifications: Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent.Similarity: Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg2+ rather than Ca2+. |
Immunogen | Immunogen: A synthesized peptide derived from human RAB11FIP5 Subcellular Location: Cytoplasm. Recycling Endosome Membrane. Mitochondrion Membrane. Tissue Specificity: Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas. Predicted Cross Reactivity: Pig, Bovine, Horse, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Dog (100%) |
Other Names | [GAF 1; Gaf-1; GAF1; gamma SNAP associated factor 1; Gamma-SNAP-associated factor 1; KIAA0857; Phosphoprotein pp75; pp75; RAB11 family interacting protein 5 (class I); Rab11 family-interacting protein 5; Rab11 FIP5; Rab11 interacting protein; Rab11 interacting protein Rip11; Rab11-FIP5; Rab11-interacting protein Rip11; Rab11fip5; RFIP5_HUMAN; RIP11] |
Gene, Accession # | [RAB11FIP5], Gene ID: 26056, NCBI: NP_056285.1, UniProt: Q9BXF6 |
Catalog # | MBS9610112 |
Price | $240, $280 |
Order / More Info | RAB11FIP5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |