TAK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTAK1
Clone[3G1-C4-E10]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, monkey
IsotypeIgG2b
Formataffinity purified
Size0.1 mL
Concentration1.8mg/ml
ApplicationsWestern Blot (WB)
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DescriptionEntrez Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. UniPort Summary Function: Serine/threonine kinase whic
ImmunogenImmunogen: Purified recombinant human TAK1 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of TAK1 and does not cross-react with related proteins. Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Other Names[M3K7_HUMAN; MAP3K 7; Map3k7; MEKK7; Mitogen activated protein kinase kinase kinase 7; Mitogen-activated protein kinase kinase kinase 7; TAK1; TGF beta activated kinase 1; TGF-beta-activated kinase 1; TGF1a; Transforming growth factor beta activated kinase 1; Transforming growth factor-beta-activated kinase 1], [MAP3K7; CSCF; FMD2; TAK1; MEKK7; TGF1a]
Gene, Accession #[TAK1], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318
Catalog #MBS475577
Price$335
Order / More InfoTAK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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