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Antigenic Specificity | Desmin (Muscle Cell Marker) |
Clone | [DES/2960R] |
Host Species | Rabbit |
Reactive Species | human, rat, hamster, chicken. |
Isotype | IgG |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of norm |
Immunogen | Immunogen: Recombinant full-length human DES protein Positive Control: SJRH30 Cells. Uterus or Leiomyosarcoma |
Other Names | [CMD1I; CSM1; CSM2; DES; Intermediate filament protein] |
Gene, Accession # | [DES], Gene ID: 1674, NCBI: NP_001918.3, UniProt: P17661 |
Catalog # | MBS4380542 |
Price | $190, $340, $340 |
Order / More Info | Desmin (Muscle Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Altmannsberger M, et al. Am J Pathol. 1985; 118:85-95. |