TDP43 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TDP43 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: At least two isoforms are known to exist for this protein; this TDP43 antibody only recongizes the longer of the two isoforms. TDP43 Antibody: TDP43 was initially identified as a novel cellular protein that bound to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3'splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). |
| Immunogen | Immunogen: TDP43 antibody was raised against a 18 amino acid synthetic peptide from near the center of human TDP43. Buffer: TDP43 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TDP43; ALS10; TDP-43; TDP43; TAR DNA-binding protein 43; TAR DNA binding protein], [TARDBP; TARDBP; ALS10; TDP-43; TDP43; TDP-43] |
| Gene, Accession # | [TARDBP], Gene ID: 23435, NCBI: ABO32290, UniProt: Q13148 |
| Catalog # | MBS150155 |
| Price | $375 |
| Order / More Info | TDP43 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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