RBL2 (N-term), 165-194 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RBL2 (N-term), 165-194 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the N-terminal region of human RBL2. RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2 |
| Immunogen | n/a |
| Other Names | [Retinoblastoma-like protein 2; 130 kDa retinoblastoma-associated protein; p130; Retinoblastoma-related protein 2; RBR-2; pRb2; RBL2; RB2] |
| Gene, Accession # | [RBL2], Gene ID: 5934, NCBI: NP_005602.3, UniProt: Q08999 |
| Catalog # | MBS9206000 |
| Price | $165, $370 |
| Order / More Info | RBL2 (N-term), 165-194 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Schaffer, B.E., et al. Cancer Res. 70(10):3877-3883(2010) Barrow-Laing, L., et al. Virology 400(2):233-239(2010) Lu, F., et al. J. Virol. 84(6):2697-2706(2010) Jowett, J.B., et al. Diabetes 59(3):726-732(2010) Cunningham, J.M., et al. Br. J. Cancer 101(8):1461-1468(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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