CDK5 (N-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CDK5 (N-term) |
| Clone | [2E8-F9-B7-C11] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, monkey |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the cyclins. Although there are 12 different cdk genes, only 5 have been shown to directly drive the cell cycle (Cdk1, -2, -3, -4, and -6). Following extracellular mitogenic stimuli, cyclin D gene expression is upregulated. Cdk4 forms a complex with cyclin D and phosphorylates Rb protein, leading to liberation of the transcription factor E2F. E2F induces transcription of genes including cyclins A and E, DNA polymerase and thymidine kinase. Cdk4-cyclin E complexes form and initiate G1/S transition. Subsequently, Cdk1-cyclin B complexes form and induce G2/M phase transition. Cdk1-c |
| Immunogen | Immunogen: Purified recombinant human CDK5 (N-terminus) protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of CDK5 (N-terminus) and does not cross-react with related proteins. Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain. UniPort Summary Function: Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can p |
| Other Names | [Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit], [PSSALRE] |
| Gene, Accession # | [CDK5], Gene ID: 1020, NCBI: NP_001157882.1, UniProt: Q00535 |
| Catalog # | MBS475069 |
| Price | $335 |
| Order / More Info | CDK5 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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