flip (IN) (I-flICE) (flICE Inhibitory Protein) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityflip (IN) (I-flICE) (flICE Inhibitory Protein)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionApoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively1,2. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP3-7. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and ?10, and potently inhibits apoptosis induced by all known
ImmunogenImmunogen: Synthetic peptide corresponding to amino acids 447 to 464 of the C-terminal of the human FLIP /FLIPL form.
Other Names[Casper; I-FLICE; FLAME-1; CASH; CLARP C-terminal], [Casp8ap2; Casp8ap2; FLASH; AA387232; mKIAA1315; D4Ertd659e; Flash]
Gene, Accession #Gene ID: 26885, NCBI: NP_001116450.1, UniProt: Q9WUF3
Catalog #MBS395728
Price$510
Order / More Infoflip (IN) (I-flICE) (flICE Inhibitory Protein) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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