Edit |   |
---|---|
Antigenic Specificity | STAP-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STAP-2 antibody detects endogenous levels of total STAP-2. Function: Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.Subunit Structure: Interacts with PTK6 and CSF1R.Post-translational Modifications: Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC. |
Immunogen | Immunogen: A synthesized peptide derived from human STAP-2 Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. Predicted Cross Reactivity: Pig, Bovine, Sheep, Dog Similarity: Pig (89%), Bovine (100%), Sheep (89%), Dog (89%) |
Other Names | [BKS; Breast tumor kinase substrate; Brk kinase substrate; BRK substrate; Signal transducing adaptor protein 2; Signal-transducing adaptor protein 2; Ssignal transducing adaptor family member 2; STAP 2; STAP-2; STAP2; STAP2_HUMAN] |
Gene, Accession # | [STAP-2], Gene ID: 55620, NCBI: NP_001013863.1, UniProt: Q9UGK3 |
Catalog # | MBS9602944 |
Price | $240, $280 |
Order / More Info | STAP-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |