TNFRSF21 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TNFRSF21 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21; this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Negatively regulates oligodendrocyte survival, |
| Immunogen | Immunogen: Recombinant Human Tumor necrosis factor receptor superfamily member 21 protein (371-655AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5866 / sc-13106 / sc-25772 |
| Other Names | [Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358), TNFRSF21, DR6], [TNFRSF21; TNFRSF21; DR6; CD358; BM-018; DR6] |
| Gene, Accession # | [TNFRSF21], Gene ID: 27242, NCBI: NP_055267.1, UniProt: O75509 |
| Catalog # | MBS1497608 |
| Price | $120, $160 |
| Order / More Info | TNFRSF21 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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