LRRTM3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLRRTM3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: At least two isoforms of LRRTM3 are known to exist; this antibody will only detect the larger isoform. The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) a
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 18 amino acid peptide near the carboxy terminus of human LRRTM3.
Other Names[Leucine-rich repeat transmembrane neuronal protein 3]
Gene, Accession #[LRRTM3], Gene ID: 347731, NCBI: NP_821079
Catalog #MBS9403316
Price$320
Order / More InfoLRRTM3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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