Human NCSTN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman NCSTN
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionNicastrin (NCST, or NCT), a single-pass membrane glycoprotein that harbors a large extracellular domain, is an essential component of the gamma-secretase complex. Several lines of evidence indicate that the members of these complexes could also contribute to the control of cell death. NCT controls cell death via phosphoinositide 3-kinase/Akt and p53-dependent pathways and that this function remains independent of the activity and molecular integrity of the gamma-secretase complexes. Increasing evidences have shown that Nicastrin/NCSTN plays a crucial role in gamma-cleavage of the amyloid precursor protein (APP). The glycoprotein Nicastrin is an essential component of the gamma-secretase complex, a high molecular weight complex which also co
ImmunogenImmunogen: Recombinant Human Nicastrin/NCSTN Protein Buffer: This antibody was obtained from a rabbit immunized with purified, recombinant Human Nicastrin/NCSTN (rh Nicastrin/NCSTN; NP 056146.1; Met 1-Glu 669).
Other Names[nicastrin isoform 2; Nicastrin; nicastrin; nicastrin]
Gene, Accession #[NCSTN ], Gene ID: 23385
Catalog #MBS2544189
Price$215, $330, $500
Order / More InfoHuman NCSTN Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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