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Antigenic Specificity | Chicken CD8a-PE/CY5 |
Clone | [CT-8] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgG1, kappa |
Format | PE-Cy5 conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Identification and enumeration of CD8+cells by Flow Cytometry 2, Identification of CD8+ T cells in acetone-fixed, Frozen tissue sections4, Immunoprecipitation 2 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: alpha chain (34-kDa) of chicken CD8. In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8alpha- and CD8beta-chains, a relatively large proportion of the CD8+ TCR-gammadelta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR-gammadelta CD8alphabeta cells in the chicken that is not found in rodents.1,3 Chicken CD8 is expressed on approximately 80% of thym |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS670297 |
Price | $320 |
Order / More Info | Chicken CD8a-PE/CY5 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Tregaskes, C.A., F. Kong, E. Paramithiotis, C.-L. Chen, M.J.H. Ratcliffe, T. F. Davison, and J.R. Young. 1995. J. Immunol. 154:4485.2. Chan, M.L., C.-L. Chen, L. Ager, and M.D. Cooper. 1988. J. Immunol. 140:2133.3. Cooper, M.D., R.P. Bucy, and C.-L. Chen. 1990. In: The Avian Model in Developmental Biology: From Organism to Genes. Editions du CNRS, pp. 239-249.4. Chen, C.H. 1996. Personal communication. |