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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |
Immunogen | Immunogen: Toll-like receptor 4 |
Other Names | [ARMD10; CD284; hToll; TLR4; TOLL; toll like receptor 4] |
Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206 |
Catalog # | MBS7607358 |
Price | $265 |
Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |