CD64 [H22] Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD64 [H22] |
| Clone | [H22] |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | Protein A purified |
| Size | 0.2 mg |
| Concentration | 1 mg/ml |
| Applications | CM-ELISA (EIA), Flow Cytometry (FC/FACS), Toxicity Assays, Competition Studies |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This immunotoxin is specific for human CD64, and specifically an epitope outside the Fc binding domain. The binding activity of the VH/VL antibody format was unaffected by fusion of the m22(scFv) coding regions to the truncated ETA coding sequences. Recombinant monoclonal antibody to CD64. Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the hybridoma H22. This recombinant antibody was prepared by cloning the single chain fragment (scFv) derived from the murine anti-human CD64 mAb m22 into the bacterial expression vector pBM1.1, and fusing it to a deletion mutant of Pseudomonas exotoxin A (ETA). |
| Immunogen | Immunogen: This recombinant antibody was prepared by cloning the single chain fragment (scFv) derived from the murine anti-human CD64 mAb m22 into the bacterial expression vector pBM1.1, and fusing it to a deletion mutant of Pseudomonas exotoxin A. |
| Other Names | [High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRI], [FCGR1A; FCGR1A; CD64; FCRI; CD64A; IGFR1; FCG1; FCGR1; IGFR1; IgG Fc receptor I; FcRI; FcgammaRIa] |
| Gene, Accession # | [CD64], Gene ID: 2209, NCBI: NP_000557.1, UniProt: P12314 |
| Catalog # | MBS488344 |
| Price | $425 |
| Order / More Info | CD64 [H22] Antibody from MYBIOSOURCE INC. |
| Product Specific References | Guyre et al., Tur et al. Monoclonal antibodies that bind to distinct epitopes on Fc gamma RI are able to trigger receptor function & Recombinant CD64-Specific Single Chain Immunotoxin Exhibits Specific Cytotoxicity against Acute Myeloid Leukemia Cells Journal of immunology, 1 September 1989, Vol.143(5), pp.1650-5 & CANCER RESEARCH 63, 8414-8419, December 1, 2003 PMID: |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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