Human Poly(A)-specific ribonuclease PARN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Poly(A)-specific ribonuclease PARN
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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Description3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. Interacts with both the 3'-end poly(A) tail and the 5'-end cap structure during degradation, the interaction with the cap structure being required for an efficient degradation of poly(A) tails. Involved in nonsense-mediated mRNA decay, a critical process of selective degradation of mRNAs that contain premature stop codons. Also involved in degradation of inherently unstable mRNAs that contain AU-rich ele
ImmunogenImmunogen: Recombinant human Poly(A)-specific ribonuclease PARN protein
Other Names[PAM16 MAGMAS; TIM16; TIMM16 CGI-136]
Gene, Accession #Gene ID: 5073, NCBI: NP_001127949.1, UniProt: O95453
Catalog #MBS7000840
Price$160, $235
Order / More InfoHuman Poly(A)-specific ribonuclease PARN Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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