Edit |   |
---|---|
Antigenic Specificity | Human Semaphorin 3C |
Clone | [29U11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Semaphorins are a large group of structurally related secreted, GPI-anchored and transmembrane cell signaling molecules. There are 8 major classifications (1-7) of Semaphorins characterized by the existence of a conserved 500 amino acid SEMA domain at the amino terminus. Classes 3,4,6, and 7 are found in vertebrates only, whilst class 5 is found in both vertebrates and invertebrates. Each class is then divided into additional subgroups based on shared structural characteristics. Semaphorins primarily function as axon growth cone guidance factors during neuronal development. Semaphorin 3A acts as a chemo-repellent to axons, and an inhibitor of the growth of axons by signaling through receptors, Neuropilin-1and Plexin-A. Recombinant human Sem |
Immunogen | Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with human recombinant protein of Semaphorin 3C. Antigen: recombinant human Semaphorin 3C. Reconstitution Buffer: PBS (sterile). |
Other Names | [Sema3c; SemE; Semae; 1110036B02Rik], [SEMA3C; SEMA3C; SemE; SEMAE; SEMAE; Sema E] |
Gene, Accession # | Gene ID: 10512, NCBI: NP_006370.1, UniProt: Q99985 |
Catalog # | MBS692191 |
Price | $490 |
Order / More Info | Human Semaphorin 3C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |