AKR1C1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AKR1C1 |
| Clone | [AT6D10] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-andorstandiol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstnionl, respectively. |
| Immunogen | Immunogen: Recombinant human AKR1C1 (1-323aa) purified from E. coli |
| Other Names | [Aldo-keto reductase family 1 member C1; 20-alpha-HSD; DD1/DD2; HBAB; DDH; DDH1; Aldo-keto reductase family 1; member C1 20 alpha (3 alpha) hydroxysteroid dehydrogenase; 20 alpha hydroxysteroid dehydrogenase; 2ALPHAHSD; AK1C1; MBAB; Aldo keto reductase family 1 member C1; C9; Chlordecone reductase homolog; Chlordecone reductase homolog HAKRC; DD1; Dihydrodiol dehydrogenase 1; Dihydrodiol dehydrogenase 1/2; H37; HAKRC; Hepatic dihydrodiol dehydrogenase; High affinity hepatic bile acid-binding protein; Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase; Type II 3 alpha hydroxysteroid dehydrogenase,], [AKR1C1; AKR1C1; C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD; DDH; DDH1; 20-alpha-HSD; DD1/DD2; HBAB] |
| Gene, Accession # | [AKR1C1], Gene ID: 1645, NCBI: NP_001344, UniProt: Q04828 |
| Catalog # | MBS200203 |
| Price | $240, $315 |
| Order / More Info | AKR1C1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | L.C. Giudice, et al. (2004) Lancet. 3644: 1789-1799; P.G. Hompes, et al. (2007) Gynecol. Endocrinol. 23: 5-12.; K.J. Berkley, et al. (2005) Science 308: 1587-1589. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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