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Antigenic Specificity | KIAA1967 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total KIAA1967 protein. Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Pl |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human KIAA1967. |
Other Names | [Protein KIAA1967; Deleted in breast cancer gene 1 protein; DBC.1; DBC-1; p30 DBC] |
Gene, Accession # | [KIAA1967], Gene ID: 57805, NCBI: NP_066997.3, UniProt: Q8N163 |
Catalog # | MBS9405126 |
Price | $200, $255 |
Order / More Info | KIAA1967 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |