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Antigenic Specificity | ACTA1 |
Clone | [337CT30.10.1] |
Host Species | Mouse |
Reactive Species | human (predicted reactivity: bovine, chicken, mouse, porcine, rabbit, rat) |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ACTA1 monoclonal antibody is generated from mouse immunized with ACTA1 recombinant protein. The product encoded by this gene belongs to the actinfamily of proteins, which are highly conserved proteins that play arole in cell motility, structure and integrity. Alpha, beta andgamma actin isoforms have been identified, with alpha actins beinga major constituent of the contractile apparatus, while beta andgamma actins are involved in the regulation of cell motility. Thisactin is an alpha actin that is found in skeletal muscle. Mutationsin this gene cause nemaline myopathy type 3, congenital myopathywith excess of thin myofilaments, congenital myopathy with cores,and congenital myopathy with fiber-type di |
Immunogen | n/a |
Other Names | [Actin; alpha skeletal muscle; Alpha-actin-1; ACTA1; ACTA] |
Gene, Accession # | [ACTA1], Gene ID: 58, NCBI: NP_001091.1, UniProt: P68133 |
Catalog # | MBS9200176 |
Price | $370 |
Order / More Info | ACTA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010) : Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010) Yu, G., et al. J Clin Neurosci 17(6):766-769(2010) Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010) : Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010) |