Edit |   |
---|---|
Antigenic Specificity | Leptin Receptor |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human Leptin Receptor. Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus. |
Other Names | [Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295; LEPR; DB; OBR], [LEPR; LEPR; OBR; OB-R; CD295; LEP-R; LEPRD; DB; OBR; LEP-R; OB-R] |
Gene, Accession # | [LEPR], Gene ID: 3953, NCBI: NP_001003679.1, UniProt: P48357 |
Catalog # | MBS179282 |
Price | $160, $340, $340 |
Order / More Info | Leptin Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |